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pH switchable tag

pH switchable tag for easy protein purification

Kurzbeschreibung

The technology discloses a 32 AA long peptide and derivatives thereof as improved tags for easy purification of recombinant proteins. Oligomerisation of the peptide was shown to be reversibly switchable by changing the pH.

Technologie

Entwicklungsstand

In experiments the responsible AA for oligomerization and for the sensitivity range of the pH switch have been elucidated.

Publikationsnummer

An EP patent application and US provisional application has been filed in 2010.

 

Anschrift

  • Campus Berlin-Buch
  • Robert-Rössle-Str. 10
  • 13125 Berlin

Ansprechpartner

 
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